Physiology papers
Pofolia’s corpus holds 73 papers from Physiology (2007–2026), each with a short summary. Below, the 20 most-cited, then the most recently added.
At a glance
- Most cited: Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues (2013, 47,290 citations).
- The 20 papers listed have 217,378 citations between them.
- 17 of the 19 with a known journal quartile appeared in a Q1 journal.
- 16 have a free full text (open access).
- Most frequent journals: Age and Ageing, American Journal of Epidemiology, British Journal of Sports Medicine.
- Published between 2012 and 2024.
Most cited
Ranked by citation count. Because citations accumulate over time, this list naturally leans towards work published a few years ago; for where the field is now, see “recently added”. How to read the signals
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
Cellular Physiology and Biochemistry · 2013 · Q3 · FWCI 460.23 · 47,290 citations · Open access
Four days of nose-only cigarette smoke exposure in mice significantly increased oxidative stress and disrupted mitochondrial function across liver, kidney, heart, and lung tissues, with lung and heart being particularly affected.
World Medical Association Declaration of Helsinki
JAMA · 2013 · Q1 · SJR 5.00 · FWCI 212.74 · 29,734 citations
The World Medical Association (WMA) has established the Declaration of Helsinki, a foundational document outlining ethical principles for medical research involving human subjects, including identifiable human material and data.
Two new Later Stone Age sites from the Final Pleistocene in the Falémé Valley, eastern Senegal
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) · 2024 · FWCI 529.79 · 24,011 citations · Open access
Two previously undiscovered Later Stone Age archaeological sites dating to the Final Pleistocene have been identified in the Falémé Valley of eastern Senegal.
Sarcopenia: revised European consensus on definition and diagnosis
Age and Ageing · 2018 · Q1 · SJR 2.00 · FWCI 479.95 · 14,163 citations · Open access
The European Working Group on Sarcopenia in Older People (EWGSOP2) has updated the definition of sarcopenia, emphasizing low muscle strength as the primary characteristic, confirmed by low muscle quantity/quality, and indicating severe sarcopenia by poor physical performance.
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
Scientific Reports · 2016 · Q1 · FWCI 423.03 · 13,291 citations · Open access
Krabbe disease causes severe damage to nerve terminals and neuromuscular junctions in mice by postnatal day 30, with peripheral nerve damage detectable even earlier at day 15, independent of demyelination.
World Health Organization 2020 guidelines on physical activity and sedentary behaviour
British Journal of Sports Medicine · 2020 · Q1 · SJR 4.00 · FWCI 525.87 · 11,193 citations · Open access
New WHO guidelines recommend 150-300 minutes of moderate or 75-150 minutes of vigorous aerobic activity weekly for adults, and 60 minutes daily for children/adolescents, alongside muscle-strengthening and reduced sedentary behavior.
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
Neurodegenerative Diseases · 2012 · Q3 · FWCI 262.79 · 10,400 citations
Chronic exposure to amyloid-beta (Aβ) oligomers, even for as short as 10 days, significantly increases tau phosphorylation and activates GSK3 in a mouse model of tauopathy, suggesting long-lasting effects on neurodegeneration.
‘Small Changes' to Diet and Physical Activity Behaviors for Weight Management
Obesity Facts · 2013 · Q1 · SJR 1.00 · FWCI 440.47 · 9,509 citations · Open access
Behavioral interventions for physical activity are often ineffective, explaining only 30% or less of behavior variability, and rarely measure or systematically change the mediating psychological variables.
Hallmarks of Cancer: New Dimensions
Cancer Discovery · 2022 · Q1 · SJR 7.00 · FWCI 906.76 · 9,260 citations · Open access
This perspective proposes refining the "hallmarks of cancer" framework by adding phenotypic plasticity and disrupted differentiation as a distinct hallmark, and nonmutational epigenetic reprogramming and polymorphic microbiomes as enabling characteristics.
The amyloid hypothesis of Alzheimer's disease at 25 years
EMBO Molecular Medicine · 2016 · Q1 · SJR 3.00 · FWCI 282.26 · 6,166 citations · Open access
Twenty-five years after its proposal, the amyloid hypothesis remains the most validated therapeutic target for Alzheimer's disease, with new evidence showing Aβ dyshomeostasis as an early, initiating factor.
Lecanemab in Early Alzheimer’s Disease
New England Journal of Medicine · 2022 · Q1 · SJR 18.00 · FWCI 494.47 · 5,328 citations · Open access
The drug lecanemab, a monoclonal antibody targeting amyloid-beta protofibrils, demonstrated a modest slowing of cognitive and functional decline by 0.45 points on the CDR-SB scale over 18 months in early Alzheimer's patients compared to placebo.
The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
Journal of Lipid Research · 2013 · Q1 · SJR 1.00 · FWCI 43.68 · 4,952 citations · Open access
Short-chain fatty acids (SCFAs), produced by gut bacteria fermenting dietary fiber, significantly influence mammalian energy metabolism through complex interactions with diet and host physiology.
Worldwide trends in insufficient physical activity from 2001 to 2016: a pooled analysis of 358 population-based surveys with 1·9 million participants
The Lancet Global Health · 2018 · Q1 · SJR 5.00 · FWCI 201.90 · 4,924 citations · Open access
Globally, 27.5% of adults were insufficiently active in 2016, with women being significantly more affected than men, and this rate remained largely stable from 2001 to 2016.
Increased Prevalence of Sleep-Disordered Breathing in Adults
American Journal of Epidemiology · 2013 · Q1 · SJR 1.00 · FWCI 138.01 · 4,608 citations · Open access
Moderate to severe sleep-disordered breathing prevalence has significantly increased in US adults over the past two decades, with relative increases ranging from 14% to 55% across different age and sex subgroups.
Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis
The Lancet Respiratory Medicine · 2019 · Q1 · SJR 7.00 · FWCI 152.11 · 4,096 citations · Open access
An estimated 936 million adults aged 30-69 globally have mild to severe obstructive sleep apnoea (OSA), with 425 million having moderate to severe OSA, based on a novel literature analysis and standardization algorithm.
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
European Respiratory Journal · 2013 · Q1 · SJR 5.00 · FWCI 80.71 · 3,946 citations · Open access
New guidelines define severe asthma as uncontrolled asthma despite high-dose controller therapy, including systemic corticosteroids, and provide recommendations for its evaluation and treatment.
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
The Journals of Gerontology Series A · 2014 · Q1 · SJR 1.00 · FWCI 84.37 · 3,841 citations
Aging is marked by chronic, low-grade inflammation, termed "inflammaging," a significant risk factor for age-related diseases and mortality, though its precise causes and causal role are still unclear.
Sedentary Behavior Research Network (SBRN) – Terminology Consensus Project process and outcome
International Journal of Behavioral Nutrition and Physical Activity · 2017 · Q1 · SJR 2.00 · FWCI 155.58 · 3,797 citations · Open access
A consensus project by the Sedentary Behavior Research Network (SBRN) has established standardized definitions for key terms related to sedentary behavior, aiming to unify research and practice.
Exercise as medicine – evidence for prescribing exercise as therapy in 26 different chronic diseases
Scandinavian Journal of Medicine and Science in Sports · 2015 · Q1 · SJR 1.00 · FWCI 80.48 · 3,512 citations
This review synthesizes evidence for using exercise as therapy across 26 chronic diseases, offering guidance on optimal exercise types and dosages for treatment.
The neuropathological diagnosis of Alzheimer’s disease
Molecular Neurodegeneration · 2019 · Q1 · SJR 6.00 · FWCI 124.83 · 3,357 citations · Open access
Alzheimer's disease diagnosis relies on identifying amyloid plaques and neurofibrillary tangles, but it's increasingly recognized as a complex mixed proteinopathy.
Recently added
Association between serum cotinine levels and prostate-related clinical endpoints
Holistic Integrative Oncology · 2026 · Q1
Higher serum cotinine, a biomarker for tobacco exposure, was independently associated with a lower free-to-total prostate-specific antigen (PSA) ratio in a nationally representative sample of 7,174 US men.
Approach to sarcopenia in older adults: a systematic review of dietary and exercise interventions in the primary care setting
BMC Geriatrics · 2026 · Q1 · SJR 1.00
Combined dietary and exercise interventions significantly improved muscle strength, physical function, and body composition in older adults with sarcopenia, according to a systematic review of six studies (444 participants in experimental groups).
Telomeres in mitosis: organization and dynamics
Nucleus · 2026 · Q1 · SJR 2.00
Telomeres, the protective caps on chromosome ends, actively participate in and are organized by key events during mammalian cell division (mitosis), including chromatin condensation and nuclear reassembly.
BenSParX: A robust explainable machine learning framework for Parkinson’s disease detection from Bengali conversational speech
Artificial Intelligence in Medicine · 2026 · Q1 · SJR 1.00 · FWCI 5.05 · 1 citations
A new framework, BenSParX, achieves 95.67% accuracy in detecting Parkinson's disease (PD) from Bengali conversational speech, using an explainable AI approach.
Machine Learning-Guided Discovery of Natural BACE1 Inhibitors with Enzymatic and Cellular Validation
ACS Omega · 2026 · Q1
Machine learning models screened a natural product library, identifying 5 compounds with IC50 < 50 μM against BACE1, including Theaflavin-3,3′-digallate which also reduced Aβ secretion in cells.
Modeling Diabetic Neuropathy: Injury Biomarkers for Early Detection Through Neuronal and Glial In Vitro Models
International Journal of Molecular Sciences · 2026 · Q1 · SJR 1.00
In vitro neuronal and glial models can identify early injury biomarkers for diabetic neuropathy (DN), a common and disabling complication of diabetes that is often detected too late.
Towards harmonised accelerometer-derived physical activity: a comparability study across wrist, thigh, and hip wear locations
International Journal of Behavioral Nutrition and Physical Activity · 2026 · Q1 · SJR 2.00
New calibration equations enable harmonisation of physical activity data derived from wrist, thigh, and hip accelerometers, showing strong correlations (0.66-0.90) and moderate-to-good agreement after calibration.
The Batten disease protein CLN8 is a stereospecific acyltransferase in bis(monoacylglycero)phosphate biosynthesis
Nature Cell Biology · 2026 · Q1 · SJR 9.00 · FWCI 10.14 · 2 citations
The endoplasmic reticulum protein CLN8, implicated in Batten disease, is a stereospecific acyltransferase that converts S,S-glycerophosphoglycerol into S,S-lysophosphatidylglycerol, a key precursor for bis(monoacylglycero)phosphate (BMP) synthesis.
Journals in this field
The journals that publish most of this field’s papers. Quartile (Q1–Q4), SJR and h-index are from SCImago Journal Rank; “in this field” is how many of the journal’s pooled papers belong here. What is a Q1 journal? · What is the h-index?
| Journal | Quartile | SJR | h-index | In this field | Summaries |
|---|---|---|---|---|---|
| New England Journal of Medicine | Q1 | 18.00 | 1275 | 2 | 376 |
| Physiological Reviews | Q1 | 11.00 | 417 | 2 | 28 |
| Nature Cell Biology | Q1 | 9.00 | 431 | 2 | 3 |
| British Journal of Sports Medicine | Q1 | 4.00 | 256 | 2 | 31 |
| Age and Ageing | Q1 | 2.00 | 185 | 2 | 12 |
| International Journal of Behavioral Nutrition and Physical Activity | Q1 | 2.00 | 172 | 2 | 13 |
| Journals of Gerontology - Series A Biological Sciences and Medical Sciences | Q1 | 1.00 | 238 | 2 | 11 |
| International Journal of Molecular Sciences | Q1 | 1.00 | 365 | 2 | 45 |
Every journal in Physiology (Q1–Q4) →
Add this field to your daily feed
Pick your interests and new work in your area arrives every day, summarised. Full summaries live in the app.
Open the app