Alzheimer s & Dementia· 2012Q1
National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
- 3,192citations
- Q1SCImago
- 2012year
Short summary
Updated guidelines for neuropathologic assessment of Alzheimer's disease (AD) now incorporate amyloid accumulation alongside neurofibrillary changes and neuritic plaques, and recognize a pre-clinical stage of AD.
AI-generated from the title and abstract; the full text is not read.
Key points
- Guidelines updated to include amyloid accumulation in AD assessment.
- Recognizes a pre-clinical stage of Alzheimer's disease.
- Establishes protocols for assessing Lewy body disease and vascular brain injury.
- Recommends standard approaches for clinico-pathologic correlation.
AI-generated from the title and abstract; the full text is not read.
Abstract
A consensus panel from the United States and Europe was convened recently to update and revise the 1997 consensus guidelines for the neuropathologic evaluation of Alzheimer's disease (AD) and other diseases of brain that are common in the elderly. The new guidelines recognize the pre-clinical stage of AD, enhance the assessment of AD to include amyloid accumulation as well as neurofibrillary change and neuritic plaques, establish protocols for the neuropathologic assessment of Lewy body disease, vascular brain injury, hippocampal sclerosis, and TDP-43 inclusions, and recommend standard approaches for the workup of cases and their clinico-pathologic correlation.
The authors' abstract, as published at the source. Alzheimer s & Dementia, 2012 · DOI ↗
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Field: Psychiatry and Mental health
Psychiatry and Mental healthMedicine