Alzheimer s & Dementia· 2014Q1
A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
- 3,071citations
- Q1SCImago
- 2014year
Short summary
Researchers have established new criteria and a conceptual framework for studying subjective cognitive decline (SCD), a potential early symptom of Alzheimer's disease (AD) in individuals with normal cognitive test performance.
AI-generated from the title and abstract; the full text is not read.
Key points
- New research criteria for subjective cognitive decline (SCD) in preclinical Alzheimer's disease (AD) have been developed.
- A conceptual framework is proposed to standardize research on SCD as a potential early AD symptom.
- Core features for reporting in SCD studies are listed to enable cross-study comparability.
- "SCD plus" features are identified that suggest a higher probability of preclinical AD.
AI-generated from the title and abstract; the full text is not read.
Abstract
There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer's disease (AD). The research on SCD in early AD, however, is limited by the absence of common standards. The working group of the Subjective Cognitive Decline Initiative (SCD-I) addressed this deficiency by reaching consensus on terminology and on a conceptual framework for research on SCD in AD. In this publication, research criteria for SCD in pre-mild cognitive impairment (MCI) are presented. In addition, a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings. Finally, a set of features is presented, which in accordance with current knowledge, increases the likelihood of the presence of preclinical AD in individuals with SCD. This list is referred to as SCD plus.
The authors' abstract, as published at the source. Alzheimer s & Dementia, 2014 · DOI ↗
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Field: Psychiatry and Mental health
Psychiatry and Mental healthMedicine