New England Journal of Medicine· 2012Q1
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- 7,822citations
- Q1SCImago
- 2012year
Short summary
Multiregion sequencing of renal carcinomas reveals branched tumor evolution where 63-69% of somatic mutations are not uniformly present across the tumor, challenging single-biopsy approaches.
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Pulmonary and Respiratory MedicineMedicine