The British Journal of Psychiatry· 2013Q1· Review
Natural history, predictors and outcomes of depression after stroke: systematic review and meta-analysis
- 974citations
- Q1SCImago
- 2013year
Short summary
Depression after stroke is prevalent (29%) and persistent, remaining stable up to 10 years, with a cumulative incidence of 39-52% within 5 years.
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Key points
- Prevalence of depression post-stroke is 29% (95% CI 25-32).
- Depression remains stable up to 10 years post-stroke, with a cumulative incidence of 39-52% within 5 years.
- Recovery rates from depression 1 year after stroke range from 15% to 57%.
- Major predictors include disability, pre-stroke depression, cognitive impairment, stroke severity, and anxiety.
- Outcomes of post-stroke depression include lower quality of life, mortality, and disability.
AI-generated from the title and abstract; the full text is not read.
Abstract
BACKGROUND: Depression after stroke is a distressing problem that may be associated with other negative health outcomes. AIMS: To estimate the natural history, predictors and outcomes of depression after stroke. METHOD: Studies published up to 31 August 2011 were searched and reviewed according to accepted criteria. RESULTS: Out of 13 558 references initially found, 50 studies were included. Prevalence of depression was 29% (95% CI 25-32), and remains stable up to 10 years after stroke, with a cumulative incidence of 39-52% within 5 years of stroke. The rate of recovery from depression among patients depressed a few months after stroke ranged from 15 to 57% 1 year after stroke. Major predictors of depression are disability, depression pre-stroke, cognitive impairment, stroke severity and anxiety. Lower quality of life, mortality and disability are independent outcomes of depression after stroke. CONCLUSION: Interventions for depression and its potential outcomes are required.
The authors' abstract, as published at the source. The British Journal of Psychiatry, 2013 · DOI ↗
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Field: Rehabilitation
RehabilitationMedicine