Pharmaceutics· 2018Q1· Review
Alginate in Wound Dressings
- 829citations
- Q1SCImago
- 2018year
Short summary
Alginate-based wound dressings, in forms like hydrogels, films, and foams, effectively absorb wound fluid, maintain moisture, and reduce bacterial infections.
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Key points
- Alginate is a biocompatible and non-toxic biopolymer suitable for wound healing.
- Alginate can be formulated into various wound dressing types: hydrogels, films, wafers, foams, and nanofibres.
- Alginate dressings absorb excess wound fluid and maintain a moist wound environment.
- These dressings help minimize bacterial infections at the wound site.
- Dressing efficacy depends on formulation components like other polymers, cross-linkers, and added agents.
AI-generated from the title and abstract; the full text is not read.
Abstract
Alginate is a biopolymer used in a variety of biomedical applications due to its favourable properties, such as biocompatibility and non-toxicity. It has been particularly attractive in wound healing applications to date. It can be tailored to materials with properties suitable for wound healing. Alginate has been used to prepare different forms of materials for wound dressings, such as hydrogels, films, wafers, foams, nanofibres, and in topical formulations. The wound dressings prepared from alginate are able to absorb excess wound fluid, maintain a physiologically moist environment, and minimize bacterial infections at the wound site. The therapeutic efficacy of these wound dressings is influenced by the ratio of other polymers used in combination with alginate, the nature of cross linkers used, the time of crosslinking, nature of excipients used, the incorporation of nanoparticles, and antibacterial agents. This review provides a comprehensive overview of the different forms of wound dressings containing alginate, in vitro, and in vivo results.
The authors' abstract, as published at the source. Pharmaceutics, 2018 · DOI ↗
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Field: Rehabilitation
RehabilitationMedicine