Oral and Maxillofacial Surgery Clinics of North America· 2026Q2· Review
Diagnostic Adjuncts and Biopsy Techniques for Oral Potentially Malignant Disorders and Oral Cavity Squamous Cell Carcinoma
- 0citations
- Q2SCImago
- 2026year
Short summary
New adjuncts like confocal microscopy, liquid biopsy, oral microbiome testing, and AI can aid in triaging oral lesions, complementing traditional biopsy and histopathology.
AI-generated from the title and abstract; the full text is not read.
Key points
- Diagnostic adjuncts can help triage abnormal oral lesions and guide biopsy site selection.
- Traditional methods like tissue autofluorescence, toluidine blue staining, and cytopathology are discussed.
- Newer adjuncts include confocal microscopy, liquid biopsy, oral microbiome testing, and artificial intelligence.
- Incisional biopsy techniques and site selection are also covered.
- Biopsy and histopathological examination remain the definitive diagnostic standard.
AI-generated from the title and abstract; the full text is not read.
Abstract
Diagnostic adjuncts for oral potentially malignant disorders such as leukoplakia or erythroplakia can aid the clinician in triaging abnormal lesions and facilitate both biopsy site selection and surgical management. No adjuncts replace gold standard biopsy and histopathological examination, and their optimal use requires training and experience. This article covers the potential applications, both in primary and expert settings, of adjuncts, such as tissue autofluorescence, toluidine blues staining, and cytopathology. It covers new and emerging adjuncts such as confocal microscopy, liquid biopsy, oral microbiome testing, and the role of artificial intelligence. Incisional biopsy site selection and techniques will also be discussed.
The authors' abstract, as published at the source. Oral and Maxillofacial Surgery Clinics of North America, 2026 · DOI ↗
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Field: Periodontics
PeriodonticsDentistry