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CA A Cancer Journal for Clinicians· 2015Q1· Review

Oral cavity and oropharyngeal squamous cell carcinoma—an update

Angela C. Chi, Terry A. Day, Brad W. Neville

Short summary

Oropharyngeal squamous cell carcinoma (OP-SCC) incidence is rising dramatically, particularly HPV-related cases, necessitating awareness of its distinct characteristics compared to oral cavity squamous cell carcinoma (OC-SCC).

AI-generated from the title and abstract; the full text is not read.

Key points

  • Rising incidence of oropharyngeal squamous cell carcinoma (OP-SCC), especially HPV-related cases.
  • Comparison of OC-SCC and OP-SCC across epidemiology, pathogenesis, presentation, assessment, management, and prognosis.
  • Importance of recognizing site-specific differences for effective patient management.
  • Need for multidisciplinary care tailored to OC-SCC and OP-SCC.

AI-generated from the title and abstract; the full text is not read.

Abstract

Oral cavity squamous cell carcinoma (OC-SCC) is the most common malignancy of the head and neck (excluding nonmelanoma skin cancer). Recent trends have shown a dramatic rise in the incidence of oropharyngeal squamous cell carcinoma (OP-SCC), with a marked increase in lesions related to human papillomavirus infection. This update presents the latest evidence regarding OC-SCC and OP-SCC. In particular, the authors compare and contrast tumors at these two sites with respect to epidemiology, etiopathogenesis, clinicopathologic presentation, clinical assessment, imaging, management, and prognosis. It is important for clinicians to be aware of differences between OC-SCC and OP-SCC so that appropriate patient education and multidisciplinary care can be provided to optimize outcomes.

The authors' abstract, as published at the source. CA A Cancer Journal for Clinicians, 2015 · DOI ↗

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