The Lancet· 2012

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

Daniel I. Swerdlow, Michael V Holmes, Karoline B Kuchenbaecker, Jorgen E L Engmann et al.

1,159citations
2012year

Short summary

Genetic variants in the IL6R gene are associated with lower odds of coronary heart disease (OR 0.95 per allele), suggesting IL6R blockade could prevent heart disease.

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Field: Rheumatology

RheumatologyMedicine