Platelet-rich plasma vs hyaluronic acid to treat knee degenerative pathology: study design and preliminary results of a randomized controlled trial

Short summary

A randomized trial found Platelet-Rich Plasma (PRP) and Hyaluronic Acid (HA) injections both improved knee pain and function at 12 months, with no statistically significant difference between them in patients with moderate osteoarthritis (OA). PRP showed a trend towards better outcomes in lower-grade degeneration (Kellgren-Lawrence score ≤ 2).

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