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Proceedings of the National Academy of Sciences· 2013Q1

Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis

Nicole Powell, Erica K. Sloan, Michael T. Bailey, Jesusa M.G. Arevalo et al.

Short summary

Social stress increases the production of immature, pro-inflammatory monocytes via beta-adrenergic signaling, leading to a conserved transcriptional response to adversity (CTRA) and potentially increasing disease risk.

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Field: Behavioral Neuroscience

Behavioral NeuroscienceNeuroscience