JAMA Psychiatry· 2014Q1· Meta-analysis
Effect of Anti-inflammatory Treatment on Depression, Depressive Symptoms, and Adverse Effects
- 943citations
- Q1SCImago
- 2014year
Short summary
A meta-analysis of 14 trials found that anti-inflammatory treatments, particularly celecoxib, significantly reduced depressive symptoms compared to placebo (SMD -0.34). No increased risk of gastrointestinal, cardiovascular, or infection-related adverse events was observed within 6-12 weeks.
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Biological PsychiatryNeuroscience