Nutrients· 2026Q1
The Anti-Osteoarthritis Effect of Medicinal and Edible Homologous Bioactive Components and Chinese Medicinal and Health Food Varieties
- 1citations
- Q1SCImago
- 2026year
Short summary
Bioactive components from edible and medicinal plants (polyphenols, flavonoids, terpenoids, alkaloids, polysaccharides) can protect cartilage and mitigate osteoarthritis progression by regulating inflammation, oxidative stress, and chondrocyte metabolism.
AI-generated from the title and abstract; the full text is not read.
Key points
- Bioactive components from edible and medicinal plants show anti-osteoarthritis effects.
- Mechanisms include regulating inflammatory signaling pathways and oxidative stress.
- These components also modulate chondrocyte metabolism and epigenetic modifications.
- MFH and MHF offer a safer, multi-target approach to OA prevention and treatment.
AI-generated from the title and abstract; the full text is not read.
Abstract
Osteoarthritis (OA) is a chronic progressive joint disease characterized by articular cartilage degeneration, subchondral bone remodeling, osteophyte formation, and synovitis. It is one of the most common disabling diseases in the middle-aged and elderly population. At present, clinical treatment is mainly based on relieving symptoms, and there is still a lack of interventions that can prevent or reverse the disease process. In recent years, bioactive components derived from medicine-food homology (MFH) and Medicinal Health Food (MHF) have received extensive attention in the prevention and treatment of osteoarthritis due to their high safety and multi-target effects. In this paper, bioactive components with anti-osteoarthritis effects in medicinal and edible homologous and medicinal health foods are systematically reviewed, including polyphenols, flavonoids, terpenoids, alkaloids, and polysaccharides. The progress of research into cartilage protection through the regulation of inflammatory signaling pathways, mitigation of oxidative stress, regulation of chondrocyte metabolism, and epigenetic modification is summarized, and the future research directions in this field are discussed.
The authors' abstract, as published at the source. Nutrients, 2026 · DOI ↗
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Field: Rheumatology
RheumatologyMedicine