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The Annual Review of Pharmacology and Toxicology· 2015Q1· Review

MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective

Jiabei Liu, Shannon J. Clough, Anthony J. Hutchinson, Ekue B. Adamah‐Biassi et al.

Short summary

Melatonin's beneficial effects on sleep, mood, and neuroprotection are mediated through MT1 and MT2 receptors, leading to the development of novel agonists like agomelatine and ramelteon for treating insomnia, circadian disorders, and other conditions.

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Field: Endocrine and Autonomic Systems

Endocrine and Autonomic SystemsNeuroscience