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Neuroscience· 2018Q2

Primary Neural Degeneration in the Human Cochlea: Evidence for Hidden Hearing Loss in the Aging Ear

Pei‐zhe Wu, Leslie D. Liberman, Kara Bennett, Victor De Gruttola et al.

Short summary

Aging humans over 60 show significant loss of peripheral auditory nerve axons (up to 60% in 7/11 subjects) that greatly exceeds inner hair cell loss, suggesting primary neural degeneration disconnected from hair cells, contributing to age-related hearing impairment without affecting audiograms.

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Field: Sensory Systems

Sensory SystemsNeuroscience