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Clinical Infectious Diseases· 2026Q1

Antimicrobial Resistance and One Health: Lessons on One Health Governance and Implementation from the Fleming Fund

Syed Shahid Abbas, Rebecca Maudling, Antoine Andremont, Yu Nandar Aung et al.

Short summary

The Fleming Fund's experience implementing One Health AMR programs across 25 countries reveals that effective programs require sustained investment beyond human health, flexible national adaptation, and explicit resourcing for multisectoral coordination.

AI-generated from the title and abstract; the full text is not read.

Key points

  • One Health should be an approach to problem framing and action, adaptable to national contexts.
  • Sustained investment beyond human health, particularly in animal and environmental sectors, is crucial for meaningful One Health AMR programs.
  • Surveillance systems must consider sector roles and needs, supported by joint interpretation capacity.
  • Explicit resourcing for multisectoral coordination and recognition of both formal governance and informal networks are essential for trust and action.

AI-generated from the title and abstract; the full text is not read.

Abstract

This paper reflects upon the experience of the Fleming Fund in designing and implementing One Health antimicrobial resistance (AMR) programs in 25 countries and identifies practical lessons for the design of future One Health programs. The Fleming Fund experience highlights key priorities for implementing One Health effectively within AMR programs-though many of the insights should be applicable to other contexts as well, such as emerging infectious diseases and health security. One Health should be treated as an approach to problem framing and action rather than a program output, with flexibility for national adaptation. Meaningful implementation requires sustained investment beyond human health, particularly in animal and environmental sectors, to avoid symbolic engagement. Surveillance systems should consider both the role of the sector and sector-specific needs, supported by capacity for joint interpretation and use of evidence. The costs of multisectoral coordination should be explicitly resourced and both formal governance mechanisms and informal professional networks recognized as essential for building trust, sustaining collaboration, and translating data into policy-relevant action.

The authors' abstract, as published at the source. Clinical Infectious Diseases, 2026 · DOI ↗

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