Chinese Medical Journal· 2025Q1· Review
Extracellular vesicles: Roles in oocytes and emerging therapeutic opportunities
- 11citations
- Q1SCImago
- 2025year
Short summary
Extracellular vesicles (EVs) are crucial for oocyte quality, transferring bioactive molecules that regulate reproductive processes and showing potential for treating ovarian pathologies.
AI-generated from the title and abstract; the full text is not read.
Key points
- Extracellular vesicles (EVs) are nanoparticles involved in transferring bioactive molecules between cells.
- EVs play a significant role in the reproductive processes of oocytes, influencing female reproductive health.
- The composition of EV cargo is altered under pathological conditions, impacting oocyte quality.
- Therapeutic applications of EVs show promise for enhancing oocyte quality and treating ovarian pathologies.
AI-generated from the title and abstract; the full text is not read.
Abstract
ABSTRACT: The production of high-quality oocytes requires precisely orchestrated intercellular communication. Extracellular vesicles (EVs) are cell-derived nanoparticles that play a vital role in the transfer of bioactive molecules, which has gained much attention in the field of diagnosis and treatment. Over the past ten years, the participation of EVs in the reproductive processes of oocytes has been broadly studied and has shown great potential for elucidating the intricacies of female reproductive health. This review provides an extensive discussion of the influence of EVs on oocytes, emphasizing their involvement in normal physiology and altered cargo under pathological conditions. In addition, the positive impact of therapeutic EVs on oocyte quality and their role in alleviating ovarian pathological conditions are summarized.
The authors' abstract, as published at the source. Chinese Medical Journal, 2025 · DOI ↗
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Field: Molecular Biology
Molecular BiologyBiochemistry, Genetics and Molecular Biology