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Nucleic Acids Research· 2025Q1

The UCSC Genome Browser database: 2026 update

Jonathan D. Casper, Matthew L Speir, Brian J. Raney, Gerardo Perez et al.

Short summary

The UCSC Genome Browser's 2026 update introduces a positional heatmap for mutation consequence data, QuickLift for cross-assembly annotation copying, and HubSpace for simplified track hub creation with dedicated storage.

AI-generated from the title and abstract; the full text is not read.

Key points

  • New positional heatmap displays functional consequences of mutations from MaveDB.
  • QuickLift tool enables copying annotation data between related genome assemblies.
  • HubSpace provides dedicated storage to simplify track hub creation and usage.
  • The UCSC Genome Browser continues its 25-year role as a central hub for genomic annotation.

AI-generated from the title and abstract; the full text is not read.

Abstract

Now in its 25th year of operation, the UCSC Genome Browser (https://genome.ucsc.edu) provides a central location for researchers around the world to display and compare annotations on assembled genomes. Highlighted updates include a positional heatmap display, used to show data on functional consequences of mutation from MaveDB; QuickLift, a tool to copy annotation data seen on one assembly for display on another related assembly; and HubSpace, an initiative to simplify the process of creating and using track hubs by providing each user account with dedicated storage on UCSC's infrastructure.

The authors' abstract, as published at the source. Nucleic Acids Research, 2025 · DOI ↗

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Field: Molecular Biology

Molecular BiologyBiochemistry, Genetics and Molecular Biology