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Cellular and Molecular Immunology· 2025Q1· Review

IL-1 family cytokines in inflammation and immunity

Cecília Garlanda, Irene Di Ceglie, Sébastien Jaillon

Short summary

The IL-1 system, comprising agonists, antagonists, and receptors, is central to innate immunity, tissue injury responses, and inflammatory diseases, with IL-1 blocking agents already approved for clinical use.

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Molecular BiologyBiochemistry, Genetics and Molecular Biology