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Materials Today Bio· 2025Q1

Isoliquiritigenin micellar microneedle for pH monitoring and diabetic wound healing

Huaqian Xue, Chen Zhang, Dini Lin, Qiancheng Gu et al.

Short summary

pH-responsive hydrogel microneedles (LSI-GCA) loaded with isoliquiritigenin (ISO) enable real-time pH monitoring and intelligent drug release, significantly accelerating diabetic wound healing by promoting angiogenesis and M2 macrophage polarization.

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Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics