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Cell Reports· 2025Q1· Review

Metabolic regulation of immunity in the tumor microenvironment

Shen Li, Yu Zhang, Huan Tong, Haozhen Sun et al.

Short summary

Tumor cells and immunosuppressive cells reprogram metabolism in the tumor microenvironment (TME), leading to nutrient competition, toxic metabolite buildup, and immune cell exhaustion, while tertiary lymphoid structures can support immune cell function.

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Field: Biological Psychiatry

Biological PsychiatryNeuroscience