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Frontiers in Cellular and Infection Microbiology· 2018Q1· Review

Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism

Jing Gao, Kang Xu, Hongnan Liu, Gang Liu et al.

Short summary

The gut microbiota significantly influences intestinal immunity by modulating tryptophan (Trp) metabolism, affecting both host and bacterial Trp metabolites. These metabolites, particularly those acting as aryl hydrocarbon receptor (AhR) ligands, are crucial for maintaining immune homeostasis.

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Field: Biological Psychiatry

Biological PsychiatryNeuroscience