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Science Advances· 2026Q1

Betel nut sucking is the earliest recorded evidence for the habitual use of a neuroactive plant drug

Adam Brumm, Nfn Fakhri, Melandri Vlok, Roger L. Papke et al.

Short summary

Skeletal remains of two preagricultural foragers from Sulawesi (Indonesia), dating to 25-16 kya, show dental pathology from habitual sucking of whole betel nuts, pushing back the earliest evidence of betel nut drug use by millennia.

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PeriodonticsDentistry