Nature· 2026Q1

Genome modelling and design across all domains of life with Evo 2

Garyk Brixi, Matthew G. Durrant, Jerome Ku, Mohsen Naghipourfar et al.

122citations
Q1SCImago
2026year

Short summary

Evo 2, a new AI foundation model trained on 9 trillion DNA base pairs, accurately predicts the functional impacts of genetic variations and generates novel genomic sequences across all domains of life with single-nucleotide resolution and a 1 million token context window.

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Molecular BiologyBiochemistry, Genetics and Molecular Biology