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Journal of Cell Science· 2026Q2

SPEF1 mediates assembly of central pair microtubule complexes in cilia of Tetrahymena

Mayukh Guha, Krishna Kumar Vasudevan, Yu‐Yang Jiang, Panagiota Louka et al.

Short summary

SPEF1 protein is essential for assembling central pair microtubule complexes in cilia, with its loss causing structural defects throughout the ciliary middle segment in Tetrahymena.

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GeneticsBiochemistry, Genetics and Molecular Biology