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Gut Microbes· 2026Q1

Strain-resolved metabolomic chemotyping identifies tryptophan and γ-glutamyl peptides as MGO-AGEs breaking postbiotic compounds for carbonyl stress mitigation

Su-Hyun Kim, Su-Hyun Kim, Seong‐Min Hong, Eun Yoo Lee et al.

Short summary

A novel strain-resolved metabolomic framework identified specific bacterial metabolite extracts, notably LFEAN031 enriched with tryptophan and γ-glutamyl peptides, that break methylglyoxal-advanced glycation end-products (MGO-AGEs) and mitigate carbonyl stress.

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Clinical BiochemistryBiochemistry, Genetics and Molecular Biology