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American Journal of Physiology-Heart and Circulatory Physiology· 2026Q1

Time-of-day variation in complement activation and endothelial glycocalyx nanomechanics in ST-elevation myocardial infarction

Isaiah J. Ting, Benedikt Fels, Kristina Kusche, Carl Vahldieck

Short summary

Complement activation and endothelial glycocalyx nanomechanics in ST-elevation myocardial infarction (STEMI) exhibit time-of-day variation, with morning STEMI patients showing higher complement markers and disrupted glycocalyx in vitro, correlating with prolonged hospitalization.

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Field: Critical Care and Intensive Care Medicine

Critical Care and Intensive Care MedicineMedicine