Critical Reviews in Analytical Chemistry· 2012Q1· Review
Past, Present, and Future of Solid Phase Extraction: A Review
- 479citations
- Q1SCImago
- 2012year
Short summary
Solid phase extraction (SPE) is a crucial, yet time-consuming, sample preparation technique in analytical chemistry, with ongoing advancements focused on selectivity, cost reduction, speed, and environmental friendliness.
AI-generated from the title and abstract; the full text is not read.
Key points
- Sample preparation, particularly extraction, is a time-consuming but critical step in analytical procedures.
- Solid phase extraction (SPE) is widely used due to its reproducibility, precision, low cost, and compatibility with other methods.
- Future directions for SPE focus on increased selectivity, reduced costs, faster processing, and environmental friendliness.
- Advancements include automation, miniaturization (e.g., multi-well SPE), and the development of new, synthesized sorbents.
AI-generated from the title and abstract; the full text is not read.
Abstract
Sample preparation of target compounds from biological, pharmaceutical, environmental, and food matrices is one of the most time-consuming steps in analytical procedures. Extraction techniques are dominant, especially those based on the processes running on the phase such as liquid-liquid and/or liquid-solid. Due to the reproducibility of data, precision, relatively low cost of the appropriate analysis, simplicity of the determination, and the possibility of direct combination of those techniques with other methods (both on-line and off-line), they have become the most widespread in routine determinations. Additionally, sample pretreatment procedures have to be more selective, cheap, quick, and environmentally friendly. Selectivity is obtained by using procedures based on immunoaffinity or molecular imprinting. Reduction of costs can be obtained by automation of the extraction procedures (automated SPE) or techniques like column-switching. Reducing at least the time for sample preparation is achieved by introducing miniaturization techniques (multi-well SPE). This review summarizes the current achievements and application of solid phase extraction (SPE). The main aim is to deal with the utilization of different types of sorbents for solid-phase extraction and emphasize the use of new synthesized sorbents as well as to bring together studies on a systematic approach to SPE method development.
The authors' abstract, as published at the source. Critical Reviews in Analytical Chemistry, 2012 · DOI ↗
Continue with a free account
Ask the paper: 3 free questions a day about this paper; save it, get its citation, new summaries every day for your field. Takeaways are Premium.
Continue free on the webSign in with Google or Apple; no card needed. You come back to this paper.
On your phone:
Field: Analytical Chemistry
Analytical ChemistryChemistry