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Scientific Reports· 2026Q1

Reversible changes in bladder urothelial permeability at low temperatures are mediated by TRPA1

Hiroki Natsuya, Shin-ichiro Karaki, Tomoe Fujita, Yoshiyuki Kojima et al.

Short summary

Low temperatures (17°C and 7°C) and TRPA1 channel activation reversibly increase bladder urothelial permeability, as evidenced by increased KCl-induced bladder contractions and decreased transepithelial electrical resistance (TEER).

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Field: Sensory Systems

Sensory SystemsNeuroscience