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Annual Review of Cell and Developmental Biology· 2013Q1· Review

TRP Channels and Pain

David Julius

Short summary

Natural irritants from plants like pepper and mint have identified three Transient Receptor Potential (TRP) ion channels (TRPV1, TRPM8, TRPA1) as key molecular detectors of thermal and chemical stimuli that initiate pain sensation.

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Field: Sensory Systems

Sensory SystemsNeuroscience