Science· 2014Q1

Tracking cancer drugs in living cells by thermal profiling of the proteome

Mikhail M. Savitski, Mikhail M. Savitski, Friedrich Reinhard, Holger Franken et al.

1,224citations
Q1SCImago
2014year

Short summary

Thermal proteome profiling (TPP) using mass spectrometry can now monitor over 7000 proteins in live cells to reveal drug-target interactions and downstream effects.

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Field: Spectroscopy

SpectroscopyChemistry