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Molecules· 2026Q1

Antitumor-Relevant Evaluation of Liquid and Microencapsulated Lepidium meyenii and Bactris gasipaes Extracts Reveals Species- and Formulation-Dependent Activity

Fabián Castillo-Solís, Juan A. Puente-Pineda, Diana Celi, Henrry M. Osorio et al.

Short summary

Lepidium meyenii liquid extract demonstrated a higher therapeutic index (2.28–3.64) in tumor cell models compared to Bactris gasipaes liquid extract (0.27–0.63 mg/mL IC50), with specific lepidine compounds in L. meyenii showing the strongest tumor-cell responses.

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