International Journal of Molecular Sciences· 2026Q1· Review

HMGB1 Post-Translational Modifications in Epstein–Barr Virus-Associated Nasopharyngeal Carcinoma: Current Evidence, Emerging Mechanistic Concepts, and Unresolved Questions

Cho Yiu Lau, Khadija Shahed Khan, Dora L.�W. Kwong, Wei Dai et al.

0citations
Q1SCImago
2026year

Short summary

Post-translational modifications (PTMs) like acetylation, phosphorylation, and lactylation influence High-mobility group box 1 (HMGB1) protein's role in Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC), potentially shifting it from a nuclear regulator to an extracellular immune mediator.

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Clinical BiochemistryBiochemistry, Genetics and Molecular Biology