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ACS Chemical Neuroscience· 2026Q1

CIRP: New Horizons for CNS Injury Biomarkers and Therapy

Na Lv, Hao Tian, Qiuyan Hao, Fengtang Yang et al.

Short summary

Extracellular cold-inducible RNA-binding protein (eCIRP) acts as a damage-associated molecular pattern (DAMP) that worsens neuroinflammation after CNS injuries, with elevated serum levels suggesting its potential as a diagnostic and prognostic biomarker.

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Field: Critical Care and Intensive Care Medicine

Critical Care and Intensive Care MedicineMedicine