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Genes· 2026Q2

Architects of Aggression: The Molecular Blueprint of Glioma Progression

David Aebisher, Jakub Tylutki, Angelika Myśliwiec, Nazarii Kozak et al.

Short summary

Glioblastoma (GBM) progression is driven by non-genetic plasticity, including transcriptomic continua, functional integration with host brain via synapses, and an immunologically cold niche, enabling rapid adaptive remodeling under therapy.

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Field: Genetics

GeneticsMedicine