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Brain· 2026Q1

The longevity gene APOE2 enhances pericyte function and reduces lipid droplets

Rais Reskiawan A Kadir, Joanna Bons, Genesis Vega Hormazabal, Prasanna Vadhana Ashok Kumaar et al.

Short summary

The APOE2 gene variant enhances brain pericyte function, improving blood-brain barrier integrity and reducing lipid droplet accumulation, according to studies in mice and human cell models.

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Field: Neurology (Neuroscience)

NeurologyNeuroscience