PofoliaShared via Pofolia

JAMA Otolaryngology–Head & Neck Surgery· 2026Q1

Newborn Hearing Screening in the Otoferlin Gene Therapy Era

Dana S. Guggenheim, Kathleen C.Y. Sie, Lawrence R. Lustig, Justin S. Golub

Short summary

This Viewpoint advocates for updating newborn hearing screening protocols to incorporate automated auditory brainstem response (AABR) testing for otoferlin (OTOF) gene therapy candidacy.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Current newborn hearing screening may not adequately identify candidates for OTOF gene therapy.
  • Automated auditory brainstem response (AABR) testing is proposed as a key diagnostic tool.
  • Updated screening recommendations are needed to facilitate early OTOF gene therapy intervention.
  • This approach could improve outcomes for infants with OTOF-related hearing loss.

AI-generated from the title and abstract; the full text is not read.

Abstract

The Viewpoint advocates for updates to newborn hearing screening recommendations to include automated auditory brainstem response testing to determine candidacy for otoferlin ( OTOF ) gene therapy.

The authors' abstract, as published at the source. JAMA Otolaryngology–Head & Neck Surgery, 2026 · DOI ↗

TakeawaysPremium
Ask the paperFree account

Continue with a free account

Ask the paper: 3 free questions a day about this paper; save it, get its citation, new summaries every day for your field. Takeaways are Premium.

Continue free on the web

Sign in with Google or Apple; no card needed. You come back to this paper.

On your phone:

Field: Sensory Systems

Sensory SystemsNeuroscience