Anesthesia Essays and Researches· 2014· Review
Ketamine: Current applications in anesthesia, pain, and critical care
- 394citations
- 2014year
Short summary
Ketamine, first introduced in 1970, has expanded its clinical uses beyond general anesthesia due to newly discovered neuroprotective, anti-inflammatory, and antitumor effects, alongside the utility of low-dose regimens.
AI-generated from the title and abstract; the full text is not read.
Key points
- Ketamine was introduced in 1970 as a general anesthetic for short procedures.
- New pharmacological properties have been identified, including neuroprotective, anti-inflammatory, and antitumor effects.
- The use of low-dose ketamine regimens has expanded its clinical applications.
- Current applications span anesthesia, pain management, and critical care.
AI-generated from the title and abstract; the full text is not read.
Abstract
Ketamine was introduced commercially in 1970 with the manufacturer's description as a "rapidly acting, nonbarbiturate general anesthetic" and a suggestion that it would be useful for short procedures. With the help of its old unique pharmacological properties and newly found beneficial clinical properties, ketamine has survived the strong winds of time, and it currently has a wide variety of clinical applications. It's newly found neuroprotective, antiinflammatory and antitumor effects, and the finding of the usefulness of low dose ketamine regimens have helped to widen the clinical application profile of ketamine. The present article attempts to review the current useful applications of ketamine in anesthesia, pain and critical care. It is based on scientific evidence gathered from textbooks, journals, and electronic databases.
The authors' abstract, as published at the source. Anesthesia Essays and Researches, 2014 · DOI ↗
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Field: Anesthesiology and Pain Medicine
Anesthesiology and Pain MedicineMedicine