Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial

Short summary

Tranexamic acid (TXA) treatment within 3 hours of injury reduced head injury-related death by 15% in patients with mild-to-moderate traumatic brain injury (TBI), with no significant increase in vascular occlusive events or seizures.

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