BMJ· 2012Q1· Review

Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis

Katharine Ker, Phil Edwards, Pablo Perel, H. Shakur et al.

1,010citations
Q1SCImago
2012year

Short summary

Tranexamic acid reduces the need for blood transfusions in surgery by a third (RR 0.62, P<0.001), with reliable evidence available for over 10 years, according to a meta-analysis of 129 trials (10,488 patients).

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Field: Biochemistry

BiochemistryMedicine