BioMed Research International· 2013Q2· Review
Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity
- 934citations
- Q2SCImago
- 2013year
Short summary
Natural coumarins, found in common foods and herbal remedies, exhibit a broad spectrum of pharmacological activities including anti-inflammatory, anticancer, and neuroprotective effects.
AI-generated from the title and abstract; the full text is not read.
Key points
- Coumarins are natural compounds found in various foods and herbal remedies.
- They possess a wide range of pharmacological activities, including anti-inflammatory, anticancer, and neuroprotective effects.
- Low toxicity and cost-effectiveness make coumarins attractive for further research and development.
AI-generated from the title and abstract; the full text is not read.
Abstract
Coumarin (2H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral, anticancer, antihypertensive, antitubercular, anticonvulsant, antiadipogenic, antihyperglycemic, antioxidant, and neuroprotective properties. Dietary exposure to benzopyrones is significant as these compounds are found in vegetables, fruits, seeds, nuts, coffee, tea, and wine. In view of the established low toxicity, relative cheapness, presence in the diet, and occurrence in various herbal remedies of coumarins, it appears prudent to evaluate their properties and applications further.
The authors' abstract, as published at the source. BioMed Research International, 2013 · DOI ↗
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Field: Biochemistry (Medicine)
BiochemistryMedicine