Oxidative Medicine and Cellular Longevity· 2016Q1· Review
Role of Antioxidants and Natural Products in Inflammation
- 993citations
- Q1SCImago
- 2016year
Short summary
This review outlines the inflammatory process and its cellular mechanisms, highlighting how an imbalance between free radicals and antioxidants contributes to chronic diseases.
AI-generated from the title and abstract; the full text is not read.
Key points
- Inflammation is a complex physiological response implicated in many chronic diseases.
- An imbalance between free radicals and natural antioxidants drives inflammation and tissue damage.
- Chronic inflammation is linked to diseases including diabetes, cancer, and cardiovascular disorders.
- Knowledge of inflammatory mechanisms can guide the development of natural product-based therapies.
AI-generated from the title and abstract; the full text is not read.
Abstract
Inflammation is a comprehensive array of physiological response to a foreign organism, including human pathogens, dust particles, and viruses. Inflammations are mainly divided into acute and chronic inflammation depending on various inflammatory processes and cellular mechanisms. Recent investigations have clarified that inflammation is a major factor for the progression of various chronic diseases/disorders, including diabetes, cancer, cardiovascular diseases, eye disorders, arthritis, obesity, autoimmune diseases, and inflammatory bowel disease. Free radical productions from different biological and environmental sources are due to an imbalance of natural antioxidants which further leads to various inflammatory associated diseases. In this review article, we have outlined the inflammatory process and its cellular mechanisms involved in the progression of various chronic modern human diseases. In addition, we have discussed the role of free radicals-induced tissue damage, antioxidant defence, and molecular mechanisms in chronic inflammatory diseases/disorders. The systematic knowledge regarding the role of inflammation and its associated adverse effects can provide a clear understanding in the development of innovative therapeutic targets from natural sources that are intended for suppression of various chronic inflammations associated diseases.
The authors' abstract, as published at the source. Oxidative Medicine and Cellular Longevity, 2016 · DOI ↗
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Field: Complementary and alternative medicine
Complementary and alternative medicineMedicine