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Cold Spring Harbor Perspectives in Medicine· 2017Q1· Preprint

Health Benefits of Exercise

Gregory N. Ruegsegger, Frank W. Booth

Short summary

Lifelong exercise delays the onset of 40 chronic conditions, with emerging understanding of the molecular mechanisms driving these benefits.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Lifelong exercise delays the onset of 40 chronic conditions.
  • Molecular mechanisms underlying exercise benefits are being elucidated.
  • Endurance training positively affects cardiovascular fitness and mental health.
  • Physical training involves complex polygenic interactions across cellular and tissue systems.

AI-generated from the title and abstract; the full text is not read.

Abstract

Overwhelming evidence exists that lifelong exercise is associated with a longer health span, delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is the molecular mechanisms by which exercise sustains and improves quality of life. The current review begins with two short considerations. The first short presentation concerns the effects of endurance exercise training on cardiovascular fitness, and how it relates to improved health outcomes. The second short section contemplates emerging molecular connections from endurance training to mental health. Finally, approximately half of the remaining review concentrates on the relationships between type 2 diabetes, mitochondria, and endurance training. It is now clear that physical training is complex biology, invoking polygenic interactions within cells, tissues/organs, systems, with remarkable cross talk occurring among the former list.

The authors' abstract, as published at the source. Cold Spring Harbor Perspectives in Medicine, 2017 · DOI ↗

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Field: Complementary and alternative medicine

Complementary and alternative medicineMedicine