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npj Science of Food· 2026Q1

Decoding fat-driven appetite: implications for flavor science and health-oriented food design

Kun Cui, Wenhao Pei, Fuqiang Liu, Hanyu Wang et al.

Short summary

Fat perception activates shared neurobiological pathways for reward, motivation, and energy balance, which are dysregulated in obesity, leading to overeating.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Fat perception involves shared neurobiological pathways for reward, incentive salience, and energy balance.
  • Dysregulation of these circuits in obesity amplifies maladaptive eating.
  • Deciphering these mechanisms is key for flavor engineering and product reformulation.
  • Interventions can target dietary fat preference and curb overconsumption without sacrificing enjoyment.

AI-generated from the title and abstract; the full text is not read.

Abstract

Fat perception engages overlapping neurobiological pathways—spanning taste, texture, and gut–brain signaling—that encode reward, incentive salience, and energy-balance feedback. In obesity, these circuits become dysregulated, amplifying maladaptive eating. Deciphering these mechanisms is foundational to food science: it directly informs flavor engineering, product reformulation, and microbiome-targeted interventions that can strategically reshape dietary fat preference and curb overconsumption without sacrificing enjoyment.

The authors' abstract, as published at the source. npj Science of Food, 2026 · DOI ↗

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Field: Nutrition and Dietetics

Nutrition and DieteticsNursing