Expert Review of Clinical Immunology· 2012Q2
Medication adherence in patients with rheumatoid arthritis: a critical appraisal of the existing literature
- 319citations
- Q2SCImago
- 2012year
Short summary
Medication adherence in rheumatoid arthritis (RA) patients ranges from 30-80%, with no consistent indicators for identifying nonadherence, suggesting a need for clinicians to address patient beliefs beyond practical barriers.
AI-generated from the title and abstract; the full text is not read.
Key points
- Medication adherence in RA patients varies widely, from 30% to 80%.
- No consistent indicators reliably identify patients with suboptimal adherence.
- Nonadherence can be unintentional (e.g., forgetfulness) or intentional (patient decision).
- Intentional nonadherence involves a patient's benefit-risk analysis influenced by beliefs, self-efficacy, and disease knowledge.
AI-generated from the title and abstract; the full text is not read.
Abstract
Adherence to medication in patients with rheumatoid arthritis is low, varying from 30 to 80%. Improving adherence to therapy could therefore dramatically improve the efficacy of drug therapy. Although indicators for suboptimal adherence can be useful to identify nonadherent patients, and could function as targets for adherence-improving interventions, no indicators are yet found to be consistently and strongly related to nonadherence. Despite this, nonadherence behavior could conceptually be categorized into two subtypes: unintentional (due to forgetfulness, regimen complexity or physical problems) and intentional (based on the patient's decision to take no/less medication). In case of intentional nonadherence, patients seem to make a benefit-risk analysis weighing the perceived risks of the treatment against the perceived benefits. This weighing process may be influenced by the patient's beliefs about medication, the patient's self-efficacy and the patient's knowledge of the disease. This implicates that besides tackling practical barriers, clinicians should be sensitive to patient's personal beliefs that may impact medication adherence.
The authors' abstract, as published at the source. Expert Review of Clinical Immunology, 2012 · DOI ↗
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Field: Family Practice
Family PracticeMedicine