The Journal of Experimental Medicine· 2012Q1

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4

Yvonne Junker, Sebastian Zeißig, Seong‐Jun Kim, Donatella Barisani et al.

625citations
Q1SCImago
2012year

Short summary

Wheat amylase trypsin inhibitors (ATIs) activate innate immune responses via TLR4, driving intestinal inflammation in celiac disease and potentially other immune disorders.

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Field: Gastroenterology

GastroenterologyMedicine