American Journal of Nephrology· 2017Q1· Review

Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients

Francesco Locatelli, Steven Fishbane, Geoffrey A. Block, Iain C. Macdougall

4,817citations
Q1SCImago
2017year

Short summary

Pharmacologic activation of hypoxia-inducible factors (HIFs) offers a novel approach to treating anemia in chronic kidney disease (CKD) by stimulating erythropoiesis through a transient pseudo-hypoxic state.

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Field: Hematology

HematologyMedicine