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New England Journal of Medicine· 2014Q1

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

Siddhartha Jaiswal, Pierre Fontanillas, Jason Flannick, Alisa K. Manning et al.

Short summary

Somatic mutations in blood cells, termed age-related clonal hematopoiesis, are detectable in nearly 10-18% of individuals over 70 and are linked to significantly increased risks of hematologic cancer, all-cause mortality, and cardiovascular events.

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Field: Hematology

HematologyMedicine