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Molecular Pharmaceutics· 2012Q1· Review

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

Fabienne Danhier, Aude Le Breton, Véronique Préat

Short summary

RGD peptides can selectively bind to the alpha(v)beta(3) integrin, a key molecule in tumor angiogenesis and expressed on tumor cells. This review highlights RGD-based strategies, particularly nanoparticles, for targeted cancer therapy and diagnosis.

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Field: Immunology and Allergy

Immunology and AllergyMedicine