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Journal of Experimental & Clinical Cancer Research· 2019Q1

Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology

Neel I. Nissen, M.A. Karsdal, Nicholas Willumsen

Short summary

Stromal collagens, particularly fibrillar types I, III, and V, are remodeled by cancer-associated fibroblasts (CAFs) to alter tumor microenvironment architecture, driving tumorigenesis and impacting treatment response.

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Field: Immunology and Allergy

Immunology and AllergyMedicine